“He also inherits a national security bureaucracy that has increasingly begun to ‘think big’ about strategy in places like the Middle East and Africa, and will be able to harness this team to great effect, if he chooses to do so,” said Berman.

Other looming geopolitical threats that O’Brien, who previously served as the Special Presidential Envoy for Hostage Affairs, will face in his new role are Russia and China.

Sandra Parker, the chairperson of CUFI Action Fund, the political advocacy arm of Christians United for Israel, told JNS: “CUFI enjoys a close working relationship with many officials throughout the Trump Administration, and we look forward to working with Ambassador O’Brien on strengthening the US-Israel relationship, confronting the Iranian menace, and curtailing the threat posed by terrorist organizations such as Hamas and Hezbollah.”

“Mr. O’Brien is a great friend of Israel, and is now the top-ranking Mormon in the pro-Israel Trump administration,” Zionist Organization of America National President Mort Klein told JNS. “He is also best friends with ardent Zionist US Ambassador to Germany [Richard] Grenell … And you can’t be a great friend of evangelical Christian Grenell unless you support Israel.”

O’Brien served under President George W. Bush as a US alternate delegate to the United Nations in 2005, in which he emphasized America’s commitment towards solving the Israeli-Palestinian conflict. Bolton was then the US ambassador to the world body.

“Endorsing resolutions that condemn Israeli actions, but that fail to address Palestinian actions or inactions, have real consequences,” he said then to the world body.

“The appointment of Robert O’Brien, a skilled negotiator and non-ideological foreign policy professional, to succeed John Bolton as National Security Advisor marks a significant turning point in the White House’s national security strategy to confront and prevail against robust adversaries, especially China and Iran, in an increasingly complex and dangerous international landscape,” Washington-based geopolitical strategist and diplomacy consultant John Sitilides told JNS.

Middle East Forum President Daniel Pipes expressed cautious optimism over Wednesday’s appointment.

“As expressed in his book While America Slept, Robert O’Brien has reassuringly conventional conservative views on US foreign policy,” he said. “But I worry when, as Special Presidential Envoy for Hostage Affairs, he writes that ‘we implore their captors to release the hostages as an act of humanity.’ Let’s hope he acquires a more robust outlook in his new role.”